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February 14th, 2025
Buprenorphine Addiction
What is buprenorphine?
Buprenorphine is a prescription medication primarily used to treat opioid addiction by easing withdrawal symptoms and reducing cravings. It works as a partial opioid agonist, meaning it activates opioid receptors in the brain but to a lesser degree than drugs like heroin or methadone, helping prevent misuse and dependency.
In the UK, buprenorphine is classified as a controlled substance under Schedule 3 of the Misuse of Drugs Regulations, making it illegal to possess without a prescription. It’s often given as part of a structured treatment plan in medical settings, where it helps people gradually step away from stronger opioids while managing withdrawal more comfortably.
Is buprenorphine addictive?
Buprenorphine can be addictive, even though it’s classed as having a moderate to low risk of dependency. While it’s typically prescribed to help with opioid addiction, buprenorphine still affects the brain’s opioid receptors, meaning it can create feelings of mild euphoria and relief. For some, especially those already battling addiction, this effect can be appealing.
Buprenorphine binds to opioid receptors but has a ‘ceiling effect,’ so after a certain dose, its effects don’t increase. This makes it safer than many opioids, lowering the risk of severe respiratory issues. But it still causes the brain to release dopamine, which can lead to a psychological dependency if it’s misused, as people might start relying on it for stress relief or comfort.
Over time, the body can get used to buprenorphine, leading to physical dependency. If someone suddenly stops, withdrawal symptoms can kick in, from flu-like discomfort to strong cravings. This potential for both physical and mental reliance means buprenorphine should be used carefully, ideally under medical guidance, to support recovery rather than create new challenges.